Inference

asr.GRASP

Command line version of GRASP. [Download bnkit.jar](project/graspcmd/archive/bnkit.jar)

GRASP-cmd

Command line version of GRASP. [Download bnkit.JAR](project/graspcmd/archive/bnkit_20211215.jar) [Download legacy bnkit.JAR](project/graspcmd/archive/bnkit_legacy.jar)

Identifying and engineering ancient variants of enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP)

We developed Graphical Representation of Ancestral Sequence Predictions (GRASP) to infer and explore ancestral variants of protein families with more than 10,000 members. GRASP uses partial order graphs to represent homology in very large datasets, which are intractable with current inference tools and may, for example, be used to engineer proteins by identifying ancient variants of enzymes.

Identifying and engineering ancient variants of enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP)

We developed Graphical Representation of Ancestral Sequence Predictions (GRASP) to infer and explore ancestral variants of protein families with more than 10,000 members. GRASP uses partial order graphs to represent homology in very large datasets, which are intractable with current inference tools and may, for example, be used to engineer proteins by identifying ancient variants of enzymes.

GRASP

GRASP performs ancestral sequence reconstruction | [Use GRASP now](http://grasp.scmb.uq.edu.au) | [Link to repository](http://github.com/bodenlab/grasp)

GRASP

GRASP performs ancestral sequence reconstruction | [Use GRASP now](http://grasp.scmb.uq.edu.au) | [Link to repository](http://github.com/bodenlab/grasp)