Engineering highly functional thermostable proteins using ancestral sequence reconstruction Yosephine Gumulya, Jong-Min Baek, Shun-Jie Wun, Raine E. S. Thomson, Kurt L. Harris, Dominic J. B. Hunter, James B. Y. H. Behrendorff, Justyna Kulig, Shan Zheng, Xueming Wu, Bin Wu, Jeanette E. Stok, James J. De Voss, Gerhard Schenk, Ulrik Jurva, Shalini Andersson, Emre M. Isin, Mikael Bodén, Luke Guddat, Elizabeth M. J. Gillam Oct 22, 2018 DOI Ancestral Sequence Reconstruction Related Engineering highly functional thermostable proteins using ancestral sequence reconstruction Fractional distance analysis Fractional distance analysis GRASP user guide GRASP user guide